Mutation L108F in MPXV is a ‘gain-of-function’ mutation, which most likely enhances processivity, changes sensitivity to nucleoside inhibitors, and fidelity of DNA synthesis.
The following information comes via Dr. Peter McCullough’s substack and the Kanan study.

In 2022, HHS Secretary Becerra declared US Monkeypox a public health emergency. Monkeypox occurred almost solely in gay or bisexual men with intense sexual contact. They ended up with blisters around the anus, buttocks, or mouth. The emergency ended in 2023.
The primary drug was the Bavarian Nordic Jynneos vaccine. With that and behavioral changes, the emergency dissipated.
As of January 10, 2023, HHS stopped tracking this Clade 2 subtype, resulting in 32,063 cases and 58 deaths. Most who died had advanced HIV disease.
A report by Kannan and others indicated that what happened in 2022 almost certainly occurred because of a gain-of-function mutation in one or more genes within the Monkeypox virus. The authors did not speculate whether it happened in a laboratory or nature.
Nevertheless, the lab gain-of-function should be stopped.
A new African outbreak has caused the World Health Organization to declare a global health emergency recently for Monkeypox.
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And, not a thing has been done! You all claim to read this BIBLE; but you do not comprehend it. I never read it; but I have a good memory. Now, Look, you got BOILS and PLAGUES ( In Revelation, Do your Homework) and GOD did not do it to you. YOU did it to yourselves, mankind. I have warned, Stop Gain of Function at all Costs, or Mankind will go Extinct. 1-million people who do not want Airborne Ebola on the NYSE will do the Job in 30-minutes or less. Come on, Mankind, Apply Yourselves.
Have some Pitcher Plant extract in the cupboard just in case
To flatten the curve we ask that you “rump rangers” out there stop for a couple of weeks. Yes, that means you’ll have to leave your buddy’s behind!
more fear porn idiocy. no such thing exists.
Did Bill Gates just get back from Africa? Damn that Bill, he is so busy saving the world these days. Un-elected, No degree, Not a scientist, Not a Doctor, I wonder where he gets off trying to save us all with his bio-weapons?